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Postdoctoral position in Immunology

Typ práce: hlavní pracovní poměr

We are seeking a highly motivated and creative scientist with expertise in immunology to support our internal program focused on the identification of novel STING/TMEM173 ligands.

Job Description:

Our group is involved in biological characterization of novel STING/TMEM173 agonists prepared by our Medicinal Chemistry Department. The activation of this pattern recognition receptor results in the stimulation of host innate responses, and it is believed that STING represents a good target for drug discovery efforts aiming to treat chronic hepatitis B or cancer. The successful candidate will be a member of a multidisciplinary team and be responsible for conducting key immunological studies. He or she will be performing multiplex ELISA assays, and study the effect of agonists on different population of immune cells in vitro and in vivo, and evaluate STING-dependent signaling in murine and human cells. The candidate will also have an opportunity to perform research focused on expanding our understanding of STING biology.

Located in the stunning city of Prague, our research facilities comprise a state-of-the-art instrumentation portfolio.


Applicant must have PhD in immunology. An extensive knowledge of standard immunological techniques including isolation and culturing of primary cells, lymphoproliferative assays, cell-based functional assays, and immune phenotyping by multi-parameter FACS analysis is required. Experience working with infectious materials is advantageous, but not required. Good oral and written communication skills in English are required as well as the ability to work independently.

Position is for 24 months starting from October 1st 2016 with possible extension. 

How to apply:

Please submit cover letter, CV, and contact information for 2-3 references combined into one PDF file by e-mail (see bellow).


Institute of Organic Chemistry and Biochemistry CAS, v.v.i.

Flemingovo n. 542/2, 166 10 Prague 6, Czech Republic

Kontaktní osoba:
Helena Mertlíková Kaiserová


Vloženo: 19.9.2016



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