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New vaccine approaches against viral infections

Datum: 13.4.2015 

Laboratoř molekulární biologie bakteriálních patogenů MBÚ AV ČR
Vás srdečně zve na přednášku

on sytems vaccinology of HIV and SIV in primates:

"New vaccine approaches against viral infections:
from basic concepts to preclinical studies in non-human primates""

Dr. Roger LE GRAND

CEA IDMIT, Fontenay aux Roses, Francie
 v pátek 12.06. 2014 od 13 hod
v kinosále areálu AV ČR v Praze Krči, budova A
http://www.biomed.cas.cz/indexcz.html
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Selected References:
HIV specific responses induced in nonhuman primates with ANRS HIV-Lipo-5 vaccine combined with rMVA-HIV prime or boost immunizations.
Dereuddre-Bosquet N, Baron ML, Contreras V, Gosse L, Mangeot I, Martinon F, Yousfi R, Clayette P, Levy Y, Le Grand R
Vaccine. 2015 Mar 31. pii: S0264-410X(15)00331-X. doi: 10.1016/j.vaccine.2015.03.032. [Epub ahead of print]
Detection of SIV in semen, urethra and male reproductive organs during efficient HAART.
Matusali G, Dereuddre Bosquet N, Le Tortorec A, Moreau M, Satie AP, Mahé D, Roumaud P, Bourry O, Sylla N, Bernard-Stoecklin S, Pruvost A, Le Grand R, Dejucq-Rainsford N.
J Virol. 2015 Apr 1. pii: JVI.03628-14.
Nonhuman primate models for cell-associated simian immunodeficiency virus transmission: the need to better understand the complexity of HIV mucosal transmission.
Bernard-Stoecklin S, Gommet C, Cavarelli M, Le Grand R.
J Infect Dis. 2014 Dec 15;210 Suppl 3:S660-6. doi: 10.1093/infdis/jiu536. Review.
Long-Term Control of Simian Immunodeficiency Virus (SIV) in Cynomolgus Macaques Not Associated with Efficient SIV-Specific CD8+ T-Cell Responses.
Bruel T, Hamimi C, Dereuddre-Bosquet N, Cosma A, Shin SY, Corneau A, Versmisse P, Karlsson I, Malleret B, Targat B, Barré-Sinoussi F, Le Grand R, Pancino G, Sáez-Cirión A, Vaslin B.
J Virol. 2015 Apr 1;89(7):3542-56. doi: 10.1128/JVI.03723-14. Epub 2015 Jan 14.
Cell-associated HIV mucosal transmission: the neglected pathway.
Anderson DJ, Le Grand R.
J Infect Dis. 2014 Dec 15;210 Suppl 3:S606-8. doi: 10.1093/infdis/jiu538.
Macrophage- and neutrophil-derived TNF-a instructs skin Langerhans cells to prime antiviral immune responses.
Epaulard O, Adam L, Poux C, Zurawski G, Salabert N, Rosenbaum P, Dereuddre-Bosquet N, Zurawski S, Flamar AL, Oh S, Romain G, Chapon C, Banchereau J, Lévy Y, Le Grand R, Martinon F.
J Immunol. 2014 Sep 1;193(5):2416-26. doi: 10.4049/jimmunol.1303339. Epub 2014 Jul 23.
Electroporation-mediated intradermal delivery of DNA vaccines in nonhuman primates.
Adam L, Le Grand R, Martinon F.
Methods Mol Biol. 2014;1121:309-13. doi: 10.1007/978-1-4614-9632-8_27.
Plasmacytoid dendritic cell dynamics tune interferon-alfa production in SIV-infected cynomolgus macaques.
Bruel T, Dupuy S, Démoulins T, Rogez-Kreuz C, Dutrieux J, Corneau A, Cosma A, Cheynier R, Dereuddre-Bosquet N, Le Grand R, Vaslin B.
PLoS Pathog. 2014 Jan 30;10(1):e1003915. doi: 10.1371/journal.ppat.1003915. eCollection 2014 Jan.
Semen CD4+ T cells and macrophages are productively infected at all stages of SIV infection in macaques.
Bernard-Stoecklin S, Gommet C, Corneau AB, Guenounou S, Torres C, Dejucq-Rainsford N, Cosma A, Dereuddre-Bosquet N, Le Grand R.
PLoS Pathog. 2013;9(12):e1003810. doi: 10.1371/journal.ppat.1003810. Epub 2013 Dec 12.

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